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Chediak-Higashi syndrome is another rare form of albinism that’s the result of a defect in the LYST gene.Griscelli syndrome is an extremely rare genetic disorder. There only have been of this syndrome worldwide since 1978.It occurs with albinism (but may not affect the entire body), immune problems, and neurological problems.It produces symptoms similar to OCA, but may not affect all areas of the skin.Hair is usually brown or blond with a silvery sheen. People with this syndrome have a defect in the white blood cells, increasing their risk of infections.